Isotopically Labeled Compounds
Cayman Chemical Chlorzoxazon-d3 500ug
An internal standard for the quantification of chlorzoxazone by GC- or LC-MS
Cayman Chemical NaphazolIn-d4hydrochlorIde 1mg
An internal standard for the quantification of naphazoline by GC- or LC-MS
Medchemexpress LLC Lignoceric acid-d4-2 | 1219794-61-2 | 98.0% | 1MG
Lignoceric acid-d4-2 | 1219794-61-2 | 98.0% | 1MG
Cayman Chemical NIfuroxazIde-d4 500ug
An internal standard for the quantification of nifuroxazide by GC- or LC-MS
Cambridge Isotope Laboratories 0.03 PERCENT W/V TMSP D2O 50G
0.03 percent -W/V- TMSP --2.2.3.3-D4 / 98 pct-- IN D2O --D. 99.9 pct-- 50g / Labeled CAS 7789-20-0 / Chemical Purity 99.5 pct
![Medchemexpress LLC [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, (αR,γS)-d4 | 149709-44-4 | 99.3% | 387.46 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000386966-logo.png-250.jpg){kind=logo}
Medchemexpress LLC [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, (αR,γS)-d4 | 149709-44-4 | 99.3% | 387.46 | 5 MG
Sacubitrilat-d4 is the deuterium-labeled Sacubitrilat, an active neprilysin (NEP) inhibitor. Deuteration, the incorporation of stable heavy isotopes into drug molecules, is used for quantitation during drug development and can affect pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Relugolix-d6 | 737789-87-6 | 98.8% | 629.67 | 1 MG
Relugolix-d6 is deuterium labeled Relugolix, a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. It possesses high affinity and potent antagonistic activity for human and monkey receptors and is used for the study of sex-hormone-dependent diseases, including endometriosis, uterine fibroids, and prostate cancer.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC (E)-2,3',4,5'-tetramethoxystilbene | 24144-92-1 | 99.4% | 300.35 | 1 ML
TMS ((E)-2,3′,4,5′-tetramethoxystilbene) is a selective and competitive CYP1B1 inhibitor with an IC50 of 6 nM and a Ki value of 3 nM. It shows a lesser inhibitory effect on CYP1A1 (IC50=300 nM) and CYP1A2 (IC50=3.1 μM). This methylated derivative of resveratrol possesses anti-cancer activity.
- Selective and competitive CYP1B1 inhibitor
- Possesses anti-cancer activity
- IC50 for CYP1B1 is 6 nM
- IC50 for CYP1A1 is 300 nM
- IC50 for CYP1A2 is 3.1 μM
Medchemexpress LLC Fenofibrate-d6 | 1092484-56-4 | 99.7% | 366.87 | 1 MG
Fenofibrate-d6 is the deuterium labeled version of Fenofibrate. Fenofibrate is recognized as a selective PPARα agonist with an EC50 of 30 μM. It also acts as an inhibitor of various human cytochrome P450 isoforms, demonstrating IC50s of 0.2, 0.7, 9.7, 4.8, and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated, which can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Methanol-d1 | 1455-13-6 | MFCD00044213 | >99.0% | 33.048 g/mol | CH3OD | 25 G
Methanol-d1 (CH3OD) is a deuterium-labeled methanol used as a deuterated solvent, tracer, and internal standard in analytical chemistry and spectroscopic applications. It offers high isotopic purity for NMR, mass spectrometry, and tracer studies, and is supplied with safety documentation for handling and storage.
- Deuterium-labeled methanol (CH3OD).
- CAS number 1455-13-6.
- High isotopic purity (≥99.0%).
- Suitable as an NMR solvent and internal standard.
- Useful as a tracer in isotopic labeling and analytical workflows.
- Provided with an SDS for safe handling and transport.
Medchemexpress LLC Rosuvastatin-d3 sodium | 1279031-70-7 | 99.1% | 506.54 | 5 MG
Rosuvastatin-d3 (sodium) is deuterium labeled Rosuvastatin. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Itraconazole-d3 | 1217512-35-0 | 99.6% | 708.65 | 1 MG
Itraconazole-d3 | 1217512-35-0 | 99.6% | 708.65 | 1 MG
Medchemexpress LLC Cortisone-d8 | 1257650-98-8 | 98.2% | 368.49 | 1 MG
Cortisone-d8 is the deuterium labeled Cortisone, an oxidized metabolite of Cortisol (a Glucocorticoid). It acts as an immunosuppressant and anti-inflammatory agent, and can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations. This compound is for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Undecanoic acid-d21 | 60658-40-4 | 207.42 | 100 MG
Undecanoic acid-d21 is a deuterium-labeled version of undecanoic acid, a monocarboxylic acid with antifungal properties. It functions by inhibiting the production of exocellular keratinase, lipase, and the biosynthesis of several phospholipids in *T. rubrum*. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs, making this compound useful for research applications.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits production of exocellular keratinase, lipase, and biosynthesis of phospholipids in *T. rubrum*
- Suitable for drug development studies due to potential impact on pharmacokinetic and metabolic profiles